As mentioned, trailer brakes are a must have (not an option), make sure your truck is equipped with a brake controller and it is in working condition. I would also recommend a weight distribution hitch. You can find used (almost new) towing parts on CL cheap from people upgrading to fifth wheel rigs. Make sure your seven way plug connection is in good working condition and all the trailer lights are working. Cross the safety chains, make sure they are not dragging. Make sure the breakaway brake cable is connected. Pay attention to how you place the weight load on the trailer (fore/aft). You need roughly 10% of the trailer loaded weight in tongue weight. (5000# = 500# in tongue weight)
My 2007 F150 crew cab 5.4 at 130K miles tows just fine. The 16/20 miles per gallon drops to only 10/11 miles per gallon when towing. Make sure your tires are fully inflated to the maximum limit cold. Check the date of manufacture on your trailer tires. "No More" than five years old is my limit. Trailer tires do not wear out, they age out.
Towing speed, slow down, there's a huge drop off in gas mileage above 65 mph. Not saying I do it, but 55 to 60 is a comfortable towing speed. Kick the overdrive button off on the shifter, so the transmission is not shifting back and forth frequently. On mountain grades you will be in second gear.
Only 200 miles, it will be easy peasey.
John