I guess a rule of thumb Howard would be that if it's all original and you have to use more than 1/4" of shims under any mount, something got tweaked.
I think the most I've ever seen from the factory in either an EB or a seventies pickup was about 1/8" of shims.
With so many new body panels having been welded in however, there is no hard and fast rule that I can think of. Too many variables now.
If you can get the doors to align with the rear tub, and fenders to align with the doors, the windshield frame straight to the window frames, and the hard top (if used) mounted up square to all that, I see no reason there should be a limit on how much shimming needs to be done.
Yes, it could get ugly if you need the equivalent of a whole new body cushion added to your existing one, to gain another 3/4" of space under any mounts, but I've seen it done and it has worked.
Sometimes you just need what you need. Would be nice if everything was perfect and played nice together, but it ain't always so.
Of course, if you're in a position to pull some things apart and start over, more power to ya!
But not everyone has that opportunity or ability.
Good luck!
Paul