I did a bunch of work on my pickup last fall and I had to drop the oil pan to pull my timing chain cover to get at the timing gears -
I dropped the pan as far as I could get it with leaving the rear two bolts in and I basically sprayed brake cleaner on the bottom of the block and on the gasket (to clean them off) and I only put RTV on the timing cover and put it back together.
Here is the timing cover put into place with RTV on it, the 1 piece silicone gasket stuck to it.
Here is it torqued down-
I am happy to report that I have ZERO leaks - I was a little hesitant to put everything back together dry, but it came apart dry and hadn't leaked a drop as of yet, so I'm happy with it.
RTV the bottom of the timing chain cover and leave the rest dry - worked for me, and it wasn't in the best of conditions....
Now on my EFI swap I was out of time, I had help and we wanted to get that 435 stabbed in, so we put my oil pan on with ONLY RTV, no gasket. Leaky bitch is all I gota say, leaking around the rear main, where I put half the damn tube of RTV too.
I had the engine upside down on a stand and it was perfectly clean - it didn't matter. I now get to have the displeasure of dropping my pan, cleaning it and putting in a 1 piece gasket from under the truck.... Luckily I hacked out the engine x-member so nothing will be in my way.