Also, what firing order is the cam? Not that this would help, but if it's different from what you're running that would certainly make things worse! However, from Mark's description it sounds like it's mostly the cam and not any discrepancy in firing order.
But I'm curious anyway since Comp did not see fit to post that up in the specifications for some reason. At least not that I saw.
The Edelbrock carb probably likes this type of cam even less than a Holley does. But different things can be tuned as well.
One pertinent aspect is the spring under the metering rods. The typical spring is stiff, because it's expecting a 16-22 vacuum reading. You would want to install their lowest rate spring I would think.
The result of the stiff spring and low vacuum signal is that the metering rods are always pushed up to the richest part of their range. Always enriched in other words.
But the carbs are very tunable however. Different metering rods, different jet sizes, different spring rates, and that kind of stuff.
So you may still be able to make it better, but as you're finding out, your engine is a system and all the parts have to be properly chosen to work together. The cam manufacturer's recommendations of which torque converter, which valve springs, which cylinder heads/compression ratios and all that stuff, is not a mere suggestion to get you to spend more money. They are practically gospel.
The only real exception to most of them are when the installer knows of slightly different components that might work even better. But very little will remain stock.
You certainly have a range of intake manifolds and carb sizes you can work with, but they would all be catering to a roughly 2000 to 5800 rpm power range dictated by the cam.
That cam might be cool in some applications, but only if built around it.
I think you're thinking in the right direction. Better to get a more appropriate cam than to keep trying to make the engine run better with the one you have now. You're throwing more money at it either way, but with a better goal by changing cams.
In my opinion anyway.
Paul