Even while using a 5th axis machining center, or cutters with cutting profiles used specifically for undercuts, it is more difficult to add the necessary detail to a female mold. The material draw ratio is also a challenge, even while using a contoured plug assist.
A male mold will have better draw, and allows for easier access to add the required detail. Ejecting the plastic off the mold would be quite a challenge, especially in the grill region. As stated, a multiple piece mold alleviates this issue to an extent, but adds a parting line. Some of the lexan bodies with detailed grills are a good example.