Short answer is no.
Long answer, just have to address the stuff
@Broncobowsher mentioned. But here is where it gets tricky.
1989 was a strange year for the 5.0 engine at Ford. The engine block in use was the E7TE-6015-CA casting, and it was used in both HO, and non-HO configuration. It was CAST and machined for a roller cam, but it was not available with a roller cam in the truck. The HO engine also used TRW forged pistons, where the non-HO used cast pistons. Forged pistons used 5/64 rings, and cast used 1.5 mm. While both engines are native 50 oz-in imbalance, there is every reason to believe that the target crankshaft bob-weight would have been slightly different for the two configurations. They both share the 2MAE crank.
The truck used a hydraulic flat tappet camshaft with a double roller timing chain, and no fuel pump provision. The double roller camshaft sprocket (and later silent chain sprocket) is thicker than earlier versions, and will not allow the use of a normal fuel pump eccentric. You will need to replace the camshaft pin with a longer one. I usually machine the center of the sprocket thinner to make sure the eccentric stays away from the timing cover. You can run the thin eccentric if you can find it. Or you can use an early style sprocket. The non-HO engine will have a 1-5-4 firing order, and a cast cam. The HO uses a 1-3-7 firing order, and a steel cam.
Truck engine uses E7 heads. with pedestal rockers, and flat tappet length mild steel pushrods.
You will know if you have a truck engine, because the block has the hole on the intake valley is drilled and threaded for the knock sensor. The passenger cars, and the HO did not receive a knock sensor, and the hole is not there. It doesn't really matter, because that's pretty much the only difference between blocks.
Be careful when using the roller lifter spider tray, because the non-HO might need to have the threads chased. Just don't go too deep, or you will get in to the cam bearing. (I'm not proud that I know that detail...)
It most certainly can be done. But you kinda have to wonder why you would want to.