I installed an OX locker in the front Dana 44 of my Bronco last spring. I re-used the original gears and didn't touch the pinion, so it was about as easy a diff change as you can get. I'm glad I did it, and I'd do it again, but it was a PAIN!
I describe this job as one where, if you have to ask if you can, then you probably can't. That's not to say "if you don't already know how" then you can't. There are plenty of resources to help you learn what you need to learn. But if you don't start with confidence that you can do it you'll likely get discouraged.
The only "special" tools I needed were a dial indicator (to check backlash), a caliper (to measure shim thickness), a torque wrench (to measure torque-to-turn, or preload indirectly) and a bearing puller (use was obvious).
I also used a height gage to measure the overall size and position of the assembly. To some extent that helped me get the shims close with the new diff before putting it in the first time, but in reality those measurements didn't work out that well, so I certainly wouldn't say that was necessary.
I was able to pry the diff out and pound it back in (using a hammer and a block of wood) pretty easily without a case spreader.
The bearing puller was the biggest tool issue for me. I tried using setup bearings first (getting them ready was a treat!), but after getting what I wanted there I put the real bearings on with the same shims and wasn't close. So I ended up having to press the final bearings on and off a few times. I think bearing pullers that looked like they'd work cost over $200 (maybe a lot over). I was able to make my own. But that cost might dissuade you from getting into it if this will be a one-time thing. Or find out if you can rent one somewhere.
I discussed the project starting with post #54 in my build thread if you want to know more of my project.