Take note.... as mentioned, it is not a matter of bolting in a 400hp motor and go. You *WILL* find weak spots everywhere... axlewrap will be a big deal.. so either 4-link or stiffer springs + anti-wrap device. You WILL break axles and ujoints.. so if you wheel, lan on choromoly everything + CTM style joints for the front.
I have a 393 stroked and bored 351w. I dont have near 400hp. I spin the ears off the chromoly axle shafts once a year. I have eaten up more rear ujoints due to wrap than I can count (no, I am not over torquing them.. yes, I have a wrap trap). I have broken the plug welds on the front axle and spun the tubes inside the housing (fun). I have twisted the splines off the input shaft to the transmission off the torque converter. I am in the process of swapping to RCV axles and putting in an atlas.. I already have 35 splines in the rear with a currie 9+ nodular case and other upgrades... NONE of this would be needed if I had kept with my mildly built explorer motor running MAF EFI.
Not to say this cant be done, but if I were doing it all over again, I wouldnt.
If you are wheeling and/or just want something different... I would do a high compression propane 302. Or a solid 302 with a turbo... depends on why you want the power of a coyote.
Going fast in a lifted, short wheelbase vehicle isnt always fun.