Yes, absolutely!! A good grounding scheme will have the negative battery cable bolted to the engine block. Then ground both the body and frame to the engine block.
The starter is generally the biggest current draw on the vehicle. The starter is grounded internally to the block. So it makes sense to have the negative battery cable bolt directly to the block, to provide the least resistance back to the battery. The other grounds fan out from there. Obviously, the body needs to be grounded for things like the lights, radio, etc to work. Most often, I see that ground strap from the rear of the intake manifold to the firewall. The frame also needs to be grounded. The stock fuel level sending unit is grounded to the frame. I installed a short strap from the same point on the block where the negative battery cable is mounted, over to the passenger-side frame.