Yes. Several things...
1. Your main power connector under the dash behind the ammeter could be loose, rusty or failing. This is a bullet-type push connector in the large Black wire. Might have a yellow stripe, but it's the largest wire under the dash anyway, so is pretty easy to spot.
2. The fusible link in your main power feed from the battery (same Black wire essentially) could be failing. This is the large Black wire (usually blank, but might have a Red stripe) attached to the battery side of the starter relay on the wheel well.
3. Main positive battery cable is failing. If yours isn't new, or you don't know how old it is, or it looks questionable, replace it. Don't clean it... Just replace it with a decent 4ga or larger one. They're cheap.
4. It can also be the main ground cable from the battery, but more often than not, it's the positive cable. However, here too, if yours is older, or of questionable lineage, toss it and get a new one.
Here again, 4ga or larger is a good idea. Is it mandatory? Nope. Ford got away with 6ga and it worked fine when new and no strange circumstances reared their ugly heads. But bigger is better here, up to a point, and even the larger 4ga and 2ga cables are really not that expensive these days.
Just make sure if you do change the ground cable, you either get one with it's own separate 10ga supplemental wire already molded in, or add your own so you can ground the body again (like the factory does) as well as the engine.
As far as I know, those are the only things that can cause not only a no-start situation, but where nothing else works either, including the headlights which don't go through the fuse box.
Good luck.
Paul