Well, depending on the year of your original engine, that’s as much as 200 hp more than it came with from the factory.
You might not be going crazy with it, but that’s certainly a big upgrade!
It can certainly benefit from larger headers, especially with the E Cam, which is geared a little more towards performance and lighter vehicles, but it’s not exactly gonna be choked off by the 1.5 primaries at lower rpm.
At least not at that same RPM range mentioned earlier, of between idle and 2500 RPM.
In fact, it’ll probably improve the street manners.
Leaving some power on the table? Certainly.
Enough to notice or be disappointed in? Probably not.
Did you say manual or automatic transmission? And you did say fuel injection versus carbureted?
With the manual transmission, and especially carbureted, you might actually appreciate the slightly higher, low speed scavenging of the smaller primaries.
And I know the subject was broached, but just exactly how much time do you intend to spend between 3500 and 6000 RPM?
And have you read all of the reports of Bronco owners using the E303 cams over the years?
Don’t want to scare you away from the engine, because it’s probably a good one. And maybe the issues others have had with it are all about the overall tune, rather than any shortcomings of the camshaft.
But don’t be surprised if, a few years from now, you decide you want a cam with better street manners. Or maybe just more vacuum production or fuel economy.
Then again, maybe this is all moot and you’re still young and love a lopey idle and that sound that a performance engine makes when it’s revving up!

Planning dual exhaust, or single?
What gear ratio tire size?