Leaf springs contain a lot of magic voodoo. But what you describe, yes, safe, lots of people do it. Now for the voodoo, which leaf? Few leaves ever just do lift. Spring rate, anti-wrap, etc. All part of the spring voodoo package. Just pick one, try it. see how it goes. The main leaf can't be done. You say 11 pack, so second and third are going to have to stay. The 11th I would leave as well. Something in the middle, sure. Just not one that has the spring alignment wrap, those are important.
You may need shorter centering bolts. A spring shop (lucky I have a couple here in Phoenix) has a large selection. Amazing how non-universal the center bolts are. Head diameter to fit the axle tight and not shift around, often overlooked for something as simple as it is small enough to clear the hole but not actually be a proper fit.